+-----------+-----------+-------+-----------+-----------+-----------+----------+
| Diffusion | Diffusion | AUROC |    Zt     |    Zt     |    Zf     | Zf (unif |
|   FROM    |    TO     |       | (degree-  | (uniform) | (degree-  |   orm)   |
|           |           |       | matched)  |           | matched)  |          |
+===========+===========+=======+===========+===========+===========+==========+
| Martinet  | ADSP      | 0.530 | 0.505     | 0.584     | 0.419     | 0.857    |
| only      |           |       |           |           |           |          |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
| ADSP only | Martinet  | 0.628 | 0.546     | 3.187     | -0.085    | 0.207    |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
| Martinet  | ADSP only | 0.522 | 0.500     | 0.829 *   | 0.172     | 0.928    |
| only      |           |       |           |           |           |          |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
| ADSP only | Martinet  | 0.632 | 0.901 *   | 3.073     | 0.028     | 0.403    |
|           | only      |       |           |           |           |          |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
| Martinet  | Overlappe | 0.902 | 1.395 *   | 1.300 *   | 0.686 *   | 1.177 *  |
| only      | d         |       |           |           |           |          |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
| ADSP only | Overlappe | 0.432 | -1.561 *  | -0.381 *  | -2.000 *  | -1.862 * |
|           | d         |       |           |           |           |          |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
| Overlappe | Non-overl | 0.534 | -0.335    | 1.248     | -0.768 *  | -0.908   |
| d         | apped     |       |           |           |           |          |
|           | genes in  |       |           |           |           |          |
|           | both      |       |           |           |           |          |
|           | groups    |       |           |           |           |          |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
Z-scores are computed for the experimental AUROC based on distributions of the random AUROCs
Zf : when randomizing source genes (Diffusion FROM)
Zf : when randomizing recipient genes (Diffusion TO)
Random genes are selected either uniformly or degree matched
* : Distribution of random AUROC is not Gaussian



+---------------+---------+--------+------------------+-------+
|      **       | #Mapped | #Total | Not mapped genes |       |
+===============+=========+========+==================+=======+
| Martinet Only | 46      | 47     | cDNA FLJ60385    | N/A   |
+---------------+---------+--------+------------------+-------+
| ADSP Only     | 52      | 53     | IQCF6            | N/A   |
+---------------+---------+--------+------------------+-------+
| Overlapped    | 1       | 1      |                  | NOP56 |
+---------------+---------+--------+------------------+-------+