+-----------+-----------+-------+-----------+-----------+-----------+----------+ | Diffusion | Diffusion | AUROC | Zt | Zt | Zf | Zf (unif | | FROM | TO | | (degree- | (uniform) | (degree- | orm) | | | | | matched) | | matched) | | +===========+===========+=======+===========+===========+===========+==========+ | Gene2axis | Gene1axis | 0.623 | -0.144 | 1.351 | 0.640 | 1.064 | +-----------+-----------+-------+-----------+-----------+-----------+----------+ | Gene1axis | Gene2axis | 0.701 | 0.933 | 1.987 | 0.595 | 0.535 | +-----------+-----------+-------+-----------+-----------+-----------+----------+ Z-scores are computed for the experimental AUROC based on distributions of the random AUROCs Zf : when randomizing source genes (Diffusion FROM) Zf : when randomizing recipient genes (Diffusion TO) Random genes are selected either uniformly or degree matched * : Distribution of random AUROC is not Gaussian +-----------+---------+--------+------------------+-----+ | ** | #Mapped | #Total | Not mapped genes | | +===========+=========+========+==================+=====+ | Gene2axis | 8 | 10 | B3GNTL1P1;YTHDF3 | N/A | +-----------+---------+--------+------------------+-----+ | Gene1axis | 10 | 10 | | N/A | +-----------+---------+--------+------------------+-----+