+-----------+-----------+-------+-----------+-----------+-----------+----------+
| Diffusion | Diffusion | AUROC |    Zt     |    Zt     |    Zf     | Zf (unif |
|   FROM    |    TO     |       | (degree-  | (uniform) | (degree-  |   orm)   |
|           |           |       | matched)  |           | matched)  |          |
+===========+===========+=======+===========+===========+===========+==========+
| ADNI      | Marttinen | 0.688 | 2.231     | 3.645     | 1.698     | 1.419    |
|           | _protein_ |       |           |           |           |          |
|           | randomFor |       |           |           |           |          |
|           | est       |       |           |           |           |          |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
| Marttinen | ADNI      | 0.529 | 2.365     | 0.540 *   | 1.849     | 1.978    |
| _protein_ |           |       |           |           |           |          |
| randomFor |           |       |           |           |           |          |
| est       |           |       |           |           |           |          |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
Z-scores are computed for the experimental AUROC based on distributions of the random AUROCs
Zf : when randomizing source genes (Diffusion FROM)
Zf : when randomizing recipient genes (Diffusion TO)
Random genes are selected either uniformly or degree matched
* : Distribution of random AUROC is not Gaussian



+--------------------------------+---------+--------+------------------+-----+
|               **               | #Mapped | #Total | Not mapped genes |     |
+================================+=========+========+==================+=====+
| ADNI                           | 28      | 28     |                  | N/A |
+--------------------------------+---------+--------+------------------+-----+
| Marttinen_protein_randomForest | 29      | 30     | C9orf172         | N/A |
+--------------------------------+---------+--------+------------------+-----+