+-----------+-----------+-------+-----------+-----------+-----------+----------+
| Diffusion | Diffusion | AUROC |    Zt     |    Zt     |    Zf     | Zf (unif |
|   FROM    |    TO     |       | (degree-  | (uniform) | (degree-  |   orm)   |
|           |           |       | matched)  |           | matched)  |          |
+===========+===========+=======+===========+===========+===========+==========+
| GS        | Ismael    | 0.708 | 1.989     | 2.713     | 1.722     | 0.801 *  |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
| Ismael    | GS        | 0.529 | 0.591     | 0.885     | 0.495     | 0.468    |
+-----------+-----------+-------+-----------+-----------+-----------+----------+
Z-scores are computed for the experimental AUROC based on distributions of the random AUROCs
Zf : when randomizing source genes (Diffusion FROM)
Zf : when randomizing recipient genes (Diffusion TO)
Random genes are selected either uniformly or degree matched
* : Distribution of random AUROC is not Gaussian



+--------+---------+--------+-----------------------------------+-----+
|   **   | #Mapped | #Total |         Not mapped genes          |     |
+========+=========+========+===================================+=====+
| GS     | 95      | 100    | SSPO;FAM153B;ERV3.1;ZNF735;LY6G5B | N/A |
+--------+---------+--------+-----------------------------------+-----+
| Ismael | 14      | 14     |                                   | N/A |
+--------+---------+--------+-----------------------------------+-----+