+-----------+-----------+-------+-----------+-----------+-----------+----------+ | Diffusion | Diffusion | AUROC | Zt | Zt | Zf | Zf (unif | | FROM | TO | | (degree- | (uniform) | (degree- | orm) | | | | | matched) | | matched) | | +===========+===========+=======+===========+===========+===========+==========+ | protein | Marttinen | 0.431 | -0.995 * | -0.707 | -1.223 | -1.276 | +-----------+-----------+-------+-----------+-----------+-----------+----------+ | Marttinen | protein | 0.525 | 0.461 | 0.876 | -0.415 | 0.133 | +-----------+-----------+-------+-----------+-----------+-----------+----------+ Z-scores are computed for the experimental AUROC based on distributions of the random AUROCs Zf : when randomizing source genes (Diffusion FROM) Zf : when randomizing recipient genes (Diffusion TO) Random genes are selected either uniformly or degree matched * : Distribution of random AUROC is not Gaussian +-----------+---------+--------+-----------------------------------+-----+ | ** | #Mapped | #Total | Not mapped genes | | +===========+=========+========+===================================+=====+ | protein | 95 | 100 | ERV3.1;LY6G5B;SSPO;FAM153B;ZNF735 | N/A | +-----------+---------+--------+-----------------------------------+-----+ | Marttinen | 8 | 8 | | N/A | +-----------+---------+--------+-----------------------------------+-----+