Diffusion FROM,Diffusion TO,AUROC,Zt (degree-matched),Zt (uniform),Zf (degree-matched),Zf (uniform) FAMILIAL only,REACT,0.7219525510431776,8.268,10.872,6.392,3.069 REACT only,FAMILIAL,0.9656322774285272,6.685,9.362,2.515,3.879 FAMILIAL only,REACT only,0.7099604033448107,5.827,10.047,5.648,2.803 REACT only,FAMILIAL only,0.9549856459330143,5.376,7.458,1.924,2.862 FAMILIAL only,Overlapped,0.9991090283201712,4.382,5.050 *,4.553,2.990 REACT only,Overlapped,0.9905620131255223,4.050,5.327,3.329 *,3.015 Overlapped,Non-overlapped genes in both groups,0.7500725142775035,8.353,13.296,3.136 *,2.707 Z-scores are computed for the experimental AUROC based on distributions of the random AUROCs Zf : when randomizing source genes (Diffusion FROM) Zf : when randomizing recipient genes (Diffusion TO) Random genes are selected either uniformly or degree matched * : Distribution of random AUROC is not Gaussian **,#Mapped,#Total,Not mapped genes, FAMILIAL Only,22,22,,N/A REACT Only,214,214,,N/A Overlapped,9,9,,BRCA2;MSH6;MSH2;ATM;BRCA1;RAD51C;BRIP1;BARD1;NBN