Diffusion FROM,Diffusion TO,AUROC,Zt (degree-matched),Zt (uniform),Zf (degree-matched),Zf (uniform) FAMILIAL only,STR,0.5619629309661867,0.179,2.881,0.165,0.570 STR only,FAMILIAL,0.9179812913375172,4.863,8.353,2.321,2.188 FAMILIAL only,STR only,0.5488794131239345,-0.350,1.944,-0.546,0.385 STR only,FAMILIAL only,0.9183860908197703,4.629,8.355,2.193,1.904 FAMILIAL only,Overlapped,0.9996485290288987,3.416 *,4.104,5.305,2.757 STR only,Overlapped,0.91407027281772,2.842,3.132,2.211,2.193 Overlapped,Non-overlapped genes in both groups,0.623997682352865,1.826,5.478,1.482,1.196 Z-scores are computed for the experimental AUROC based on distributions of the random AUROCs Zf : when randomizing source genes (Diffusion FROM) Zf : when randomizing recipient genes (Diffusion TO) Random genes are selected either uniformly or degree matched * : Distribution of random AUROC is not Gaussian **,#Mapped,#Total,Not mapped genes, FAMILIAL Only,27,27,,N/A STR Only,135,136,KRBOX4,N/A Overlapped,4,4,,ATM;PALB2;MSH6;BRCA2