Diffusion FROM,Diffusion TO,AUROC,Zt (degree-matched),Zt (uniform),Zf (degree-matched),Zf (uniform) Mild only,Severe,0.6311946335147286,4.501,6.989,2.368,1.815 Severe only,Mild,0.6916877275559227,4.619,6.769 *,2.818,3.004 Mild only,Severe only,0.6092328533524802,3.571,5.298,1.373 *,1.373 Severe only,Mild only,0.6462850082110673,2.495,4.830 *,1.097,1.490 Mild only,Overlapped,0.8440032348038488,4.816,4.723,3.528,3.048 Severe only,Overlapped,0.8876866610796263,5.956,5.751 *,4.033 *,4.197 Overlapped,Non-overlapped genes in both groups,0.6580722916909313,5.810,10.508,2.416,1.702 Z-scores are computed for the experimental AUROC based on distributions of the random AUROCs Zf : when randomizing source genes (Diffusion FROM) Zf : when randomizing recipient genes (Diffusion TO) Random genes are selected either uniformly or degree matched * : Distribution of random AUROC is not Gaussian **,#Mapped,#Total,Not mapped genes, Mild Only,83,83,,N/A Severe Only,188,191,COLGALT1;NLRC3;HYAL3,N/A Overlapped,19,19,,CYP2W1;CTH;MGST2;OAS3;CASP9;DPEP1;DAPK2;PGM2;CYP2A13;CYP2A7;UNC5B;SUOX;CYP2B6;CYP1A1;DDX58;CYP4F2;CYP2F1;ACY3;ABCE1