Diffusion FROM,Diffusion TO,AUROC,Zt (degree-matched),Zt (uniform),Zf (degree-matched),Zf (uniform) CovidGS only,Severe,0.6349981543978063,3.475,6.187,1.837,1.667 Severe only,CovidGS,0.7811467341629755,6.224 *,9.732,2.167,2.695 CovidGS only,Severe only,0.6294903330631161,3.195,6.002,1.959 *,1.362 Severe only,CovidGS only,0.7763059231530788,6.490,8.321,2.322,2.437 CovidGS only,Overlapped,0.9902405928709357,3.565 *,3.058,2.115,2.082 * Severe only,Overlapped,0.8947783147720109,1.306 *,2.358 *,-0.620 *,0.282 Overlapped,Non-overlapped genes in both groups,0.6057879966659583,-0.054,5.813,2.858 *,0.032 Z-scores are computed for the experimental AUROC based on distributions of the random AUROCs Zf : when randomizing source genes (Diffusion FROM) Zf : when randomizing recipient genes (Diffusion TO) Random genes are selected either uniformly or degree matched * : Distribution of random AUROC is not Gaussian **,#Mapped,#Total,Not mapped genes, CovidGS Only,72,76,ABO;MBL3P;HLA-DRB4,N/A Severe Only,197,199,COLGALT1;HYAL3,N/A Overlapped,3,3,,OAS2;DDX58;OAS3