Comparing distributions of experimental and random diffusion values (p-values for KS tests)
Seeds	Recipients	Randomize Seeds (degree-matched)	Randomize Recipients (degree-matched)	Randomize Seeds (uniform)	Randomize Recipients (uniform)
wavelet	gp2maybe	8.21e-01	9.20e-01	6.99e-02	1.22e-01
gp2maybe	wavelet	3.25e-01	5.18e-01	5.97e-12	3.67e-26



Evaluating how well wavelet genes are linked to gp2maybe genes, comparing against random

ROC results
Seeds	Recipients	AUROC	Z-score for Random Seeds (degree-matched)	Z-score for Random Recipients (degree-matched)	Z-score for Random Seeds (uniform)	Z-score for Random Recipients (uniform)
wavelet	gp2maybe	0.71	-0.48	-0.02	0.58	1.80
gp2maybe	wavelet	0.71	-0.61	-0.14	-0.09	11.08

PRC results
Seeds	Recipients	AUPRC	Z-score for Random Seeds (degree-matched)	Z-score for Random Recipients (degree-matched)	Z-score for Random Seeds (uniform)	Z-score for Random Recipients (uniform)
wavelet	gp2maybe	0.00	-0.82	0.21	0.39	1.04
gp2maybe	wavelet	0.02	0.09	-0.24	0.10	9.00

Z-scores are computed for the experimental area under ROC or PRC based on distributions of the random areas under these curves
Seeds: Genes where diffusion signal starts FROM)
Recipients: Genes that receive the diffusion signal and that are in the other validated group
Random genes are selected either uniformly or degree matched



Number of genes
**	#Total	# Mapped in the network	Not mapped genes	 
wavelet	239	236	2021-09-09 00:00:00;SOS 1;ARL 11.00
gp2maybe	6	6