Comparing distributions of experimental and random diffusion values (p-values for KS tests)
Seeds	Recipients	Randomize Seeds (degree-matched)	Randomize Recipients (degree-matched)	Randomize Seeds (uniform)	Randomize Recipients (uniform)
94_exp12	Ismael_GS	1.00e-01	1.09e-01	2.81e-02	3.00e-04
Ismael_GS	94_exp12	3.60e-02	3.11e-01	3.89e-05	1.73e-01



Evaluating how well 94_exp12 genes are linked to Ismael_GS genes, comparing against random

ROC results
Seeds	Recipients	AUROC	Z-score for Random Seeds (degree-matched)	Z-score for Random Recipients (degree-matched)	Z-score for Random Seeds (uniform)	Z-score for Random Recipients (uniform)
94_exp12	Ismael_GS	0.75	0.99	1.63	1.27	4.03
Ismael_GS	94_exp12	0.53	1.00	0.91	1.03	1.21

PRC results
Seeds	Recipients	AUPRC	Z-score for Random Seeds (degree-matched)	Z-score for Random Recipients (degree-matched)	Z-score for Random Seeds (uniform)	Z-score for Random Recipients (uniform)
94_exp12	Ismael_GS	0.00	0.28	0.22	0.78	1.77
Ismael_GS	94_exp12	0.01	0.61	0.74	0.79	1.32

Z-scores are computed for the experimental area under ROC or PRC based on distributions of the random areas under these curves
Seeds: Genes where diffusion signal starts FROM)
Recipients: Genes that receive the diffusion signal and that are in the other validated group
Random genes are selected either uniformly or degree matched



Number of genes
**	#Total	# Mapped in the network	Not mapped genes	 
94_exp12	94	94	
Ismael_GS	14	14